SCHEMBL29288484

SCHEMBL29288484

CCCCCCCCSc1ncnc(N)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.54
HTT P42858 2/20 0.54
KDM4E B2RXH2 1/20 0.54
MEN1 O00255 1/20 0.54
TSHR P16473 1/20 0.54
KMT2A Q03164 1/20 0.54
HSD17B10 Q99714 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
SMN1; SMN2 Q16637 4/20 0.51
ALDH1A1 P00352 2/20 0.51
LMNA P02545 1/20 0.51
MAPT P10636 1/20 0.51
HPGD P15428 1/20 0.51
HASPIN Q8TF76 2/20 0.43
SCN9A Q15858 2/20 0.42
SCN5A Q14524 1/20 0.42
PAK1 Q13153 1/20 0.41
NPC1 O15118 1/20 0.41
NFKB1 P19838 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284354 0.88 GAA (0.53) GAAHTTKDM4EMEN1TSHR
SCHEMBL31192703 0.86 LMNA (0.46) GAAHTTKDM4EMEN1TSHR
SCHEMBL11135378 0.80 SMN1; SMN2 (0.59) GAAHTTKDM4EMEN1TSHR
SCHEMBL22166085 0.78 HSP90AA1 (0.52) HTTKDM4ESMN1; SMN2ALDH1A1LMNA
SCHEMBL11821001 0.77 SMN1; SMN2 (0.46) GAAHTTKDM4EMEN1TSHR
SCHEMBL5586189 0.77 SMN1; SMN2 (0.46) GAAHTTKDM4EMEN1TSHR
SCHEMBL3691473 0.77 SMN1; SMN2 (0.46) GAAHTTKDM4EMEN1TSHR
SCHEMBL7055583 0.74 PAK1 (0.44) GAAHTTKDM4EMEN1TSHR
SCHEMBL26449578 0.74 KDM4E (0.57) GAAHTTKDM4EMEN1TSHR
SCHEMBL11799528 0.72 SMN1; SMN2 (0.49) GAAHTTKDM4EMEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109400543-A Triazine precursor, method for preparing triazine precursor and application of triazine precursor 暨南国际大学 2019-03-01 CN disclosed