SCHEMBL29288487

SCHEMBL29288487

CCCC(c1cc(C)cc(C)c1)c1cc(C)cc(C)c1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
ALOX15 P16050 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
TPMT P51580 1/20 0.32
TACR1 P25103 3/20 0.32
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CYP19A1 P11511 1/20 0.31
AOC3 Q16853 1/20 0.31
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25202151 0.78 ALDH1A1 (0.32) ALDH1A1TSHRTPMTTACR1CYP19A1
SCHEMBL29278635 0.76 HTT (0.33) ALDH1A1TSHRHTTNPSR1
Hydrochloric Acid SCHEMBL30492669 0.76 ALDH1A1 (0.31) ALDH1A1TSHRTPMTTACR1
SCHEMBL14607513 0.76 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL28835042 0.76 TACR1 (0.37) ALDH1A1TSHRTACR1
SCHEMBL28266226 0.76 HTT (0.37) ALDH1A1HTTNPSR1
SCHEMBL9330269 0.75 CYP19A1 (0.46) CYP2C19CYP19A1
SCHEMBL25203168 0.75 CYP19A1 (0.33) CYP19A1
SCHEMBL7202914 0.75 ESR1 (0.43) TP53CYP2D6CYP2C9ALOX15CYP2C19
Hydrochloric Acid SCHEMBL25209577 0.75 HTT (0.32) HTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109400777-A Vanadium complex and its preparation method and application based on acenaphthenequinone diimine ligand 河北师范大学 2019-03-01 CN disclosed