Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | TP53 | P04637 | 5/20 | 0.57 |
| ▸ | RAD52 | P43351 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611438 | 0.82 | POLB (0.59) | POLBKMT2ALMNAGLAGAA | |
| SCHEMBL29642054 | 0.82 | POLB (0.59) | POLBKMT2ALMNAGLAGAA | |
| SCHEMBL879558 | 0.81 | POLB (0.63) | POLBKMT2ALMNAGLAGAA | |
| SCHEMBL29361482 | 0.81 | POLB (0.63) | POLBKMT2ALMNAGLAGAA | |
| Hydrochloric Acid SCHEMBL5251194 | 0.81 | POLB (0.62) | POLBKMT2ALMNAGLAGAA | |
| SCHEMBL3265628 | 0.80 | POLB (0.61) | POLBKMT2ALMNAGLAGAA | |
| SCHEMBL11404500 | 0.79 | POLB (0.59) | POLBKMT2ALMNAGLAGAA | |
| SCHEMBL17122641 | 0.77 | POLB (0.47) | POLBKMT2ALMNAGLAGAA | |
| SCHEMBL16466463 | 0.76 | DHFR (0.51) | POLBKMT2ALMNAMAPTTP53 | |
| SCHEMBL11046169 | 0.76 | POLB (0.97) | POLBKMT2ALMNAGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109414441-A | Quinazoline and indole compounds for the treatment of medical disorders | 艾其林医药公司 | 2019-03-01 | — | — | CN | disclosed |