Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 2/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927327 | 0.85 | LMNA (0.69) | LMNAHTTSMN1; SMN2MAPK1POLB | |
| SCHEMBL4608475 | 0.83 | LMNA (0.67) | LMNAHTTSMN1; SMN2MAPK1POLB | |
| SCHEMBL15880603 | 0.81 | CA1 (0.73) | LMNAHTTSMN1; SMN2MAPK1POLB | |
| Hydrochloric Acid SCHEMBL4609744 | 0.81 | LMNA (0.65) | LMNAHTTSMN1; SMN2MAPK1POLB | |
| SCHEMBL4182162 | 0.80 | KMT2A (0.77) | LMNAHTTSMN1; SMN2MAPK1POLB | |
| SCHEMBL4608783 | 0.80 | PDE4A (0.88) | LMNAHTTSMN1; SMN2MAPK1POLB | |
| SCHEMBL24040870 | 0.79 | ALDH1A1 (0.74) | LMNAHTTSMN1; SMN2MAPK1POLB | |
| SCHEMBL4180372 | 0.79 | KMT2A (0.61) | LMNAHTTSMN1; SMN2MAPK1POLB | |
| SCHEMBL12932731 | 0.79 | SMN1; SMN2 (0.61) | LMNAHTTSMN1; SMN2MAPK1POLB | |
| SCHEMBL4609361 | 0.79 | ALDH1A1 (0.74) | LMNAHTTSMN1; SMN2MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108610304-B | Synthetic method of diaryl sultam compound | 陕西师范大学 | 2021-10-15 | — | — | CN | disclosed |