Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.36 |
| ▸ | AOC2 | O75106 | 5/20 | 0.35 |
| ▸ | MAOA | P21397 | 5/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623127 | 0.80 | SCD (0.31) | SCD | |
| SCHEMBL16499182 | 0.75 | MAOB (0.34) | MAOBAOC2MAOADAOSCD | |
| SCHEMBL7919906 | 0.74 | MAOB (0.35) | MAOBAOC2MAOADAOSCD | |
| SCHEMBL5182985 | 0.74 | CYP2C9 (0.36) | MAOBAOC2MAOADAOSCD | |
| SCHEMBL1887520 | 0.73 | HSP90AA1 (0.38) | MAOBAOC2MAOASCD | |
| SCHEMBL29416859 | 0.73 | HSP90AA1 (0.38) | MAOBAOC2MAOASCD | |
| SCHEMBL10601488 | 0.72 | MAOB (0.33) | MAOBAOC2MAOADAOSCD | |
| SCHEMBL31742548 | 0.72 | MAOB (0.33) | MAOBAOC2MAOADAOSCD | |
| SCHEMBL29288708 | 0.69 | SCD (0.32) | MAOBAOC2MAOADAOHTR2A | |
| SCHEMBL4560725 | 0.69 | SIRT1 (0.38) | MAOBMAOAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153092-B | A kind of mercaptamine base of condensed tannin replaces the preparation method of catabolite | 中国人民解放军军事医学科学院毒物药物研究所 | 2019-03-08 | — | — | CN | disclosed |