Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29153820 | 1.00 | CES2 (0.35) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL29153821 | 1.00 | CES2 (0.35) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL28597160 | 0.85 | CES2 (0.34) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL28734198 | 0.85 | CES2 (0.34) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL28597163 | 0.85 | CES2 (0.34) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL9064468 | 0.85 | CES2 (0.34) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL28162885 | 0.84 | CES2 (0.31) | CES2LMNACES1 | |
| SCHEMBL28162883 | 0.84 | CES2 (0.31) | CES2LMNACES1 | |
| SCHEMBL28975465 | 0.84 | CES2 (0.31) | CES2LMNACES1 | |
| SCHEMBL28975466 | 0.75 | CES2 (0.34) | CES2LMNACES1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1172369-B1 | Synthesis of 2-deoxy-2-fluoro-arabinose derivates | AIR PROD & CHEM (US) | 2010-09-22 | — | — | EP | claimed |
| US-6462191-B1 | DEOXOFLUORINATION OF FURANOSE; HEATING | AIR PRODUCTS AND CHEMICALS, INC. | 2002-10-08 | — | — | US | claimed |
| EP-1172369-A1 | Synthesis of 2-deoxy-2-fluoro-arabinose derivates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-01-16 | — | — | EP | claimed |
| EP-1172369-B1 | Synthesis of 2-deoxy-2-fluoro-arabinose derivates | AIR PROD & CHEM (US) | 2010-09-22 | — | — | EP | disclosed |
| US-6462191-B1 | DEOXOFLUORINATION OF FURANOSE; HEATING | AIR PRODUCTS AND CHEMICALS, INC. | 2002-10-08 | — | — | US | disclosed |
| EP-1172369-A1 | Synthesis of 2-deoxy-2-fluoro-arabinose derivates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-01-16 | — | — | EP | disclosed |