Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28734198 | 1.00 | CES2 (0.34) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL28597160 | 1.00 | CES2 (0.34) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL28597163 | 1.00 | CES2 (0.34) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL29153820 | 0.85 | CES2 (0.35) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL29153821 | 0.85 | CES2 (0.35) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL2928916 | 0.85 | CES2 (0.35) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL28975466 | 0.76 | CES2 (0.34) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL3708189 | 0.75 | CES2 (0.33) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL22206336 | 0.75 | CES2 (0.33) | CES2LMNACES1TDP1L3MBTL1 | |
| SCHEMBL28975465 | 0.75 | CES2 (0.31) | CES2LMNACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748330-A1 | L-NUCLEOSIDES FOR THE TREATMENT OF HEPATITIS B-VIRUS AND EPSTEIN-BAR VIRUS | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995020595-A1 | L-NUCLEOSIDES FOR THE TREATMENT OF HEPATITIS B-VIRUS AND EPSTEIN-BAR VIRUS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1995-08-03 | — | — | WO | disclosed |
| EP-0540686-A4 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES | US COMMERCE (US) | 1993-05-26 | — | — | EP | disclosed |
| EP-0540686-A1 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES. | US COMMERCE (US) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001700-A1 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1992-02-06 | — | — | WO | disclosed |
| EP-0145978-B1 | NUCLEOSIDE PROCESS | Bristol-Myers Company (US) | 1989-04-19 | — | — | EP | disclosed |