Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8299332 | 0.84 | RAB9A (0.54) | RAB9AMAPTALDH1A1NPC1RXFP1 | |
| SCHEMBL14581628 | 0.79 | CSF1R (0.46) | ALDH1A1LMNAKDM4E | |
| SCHEMBL27526838 | 0.79 | RAB9A (0.50) | RAB9AMAPTALDH1A1NPC1RXFP1 | |
| SCHEMBL13844328 | 0.76 | MAPT (0.43) | RAB9AMAPTALDH1A1NPC1RXFP1 | |
| SCHEMBL30117773 | 0.76 | RAB9A (0.56) | RAB9AMAPTALDH1A1NPC1RXFP1 | |
| SCHEMBL7053228 | 0.76 | RAB9A (0.56) | RAB9AMAPTALDH1A1NPC1RXFP1 | |
| SCHEMBL4099491 | 0.75 | RAB9A (0.60) | RAB9AMAPTALDH1A1NPC1RXFP1 | |
| SCHEMBL28085964 | 0.75 | SMN1; SMN2 (0.58) | RAB9AMAPTALDH1A1NPC1RXFP1 | |
| SCHEMBL3635988 | 0.75 | EGFR (0.62) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL15025570 | 0.75 | RAB9A (0.63) | RAB9AMAPTALDH1A1NPC1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104098551-B | Substituted quinazoline analog derivative as Ou Ruola kinase inhibitor | 广东东阳光药业有限公司 | 2019-03-22 | — | — | CN | disclosed |