Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29289403 | 0.84 | RAB9A (0.53) | RAB9AL3MBTL1NPC1TSHRSMN1; SMN2 | |
| SCHEMBL15025570 | 0.79 | RAB9A (0.63) | RAB9AL3MBTL1NPC1TSHRSMN1; SMN2 | |
| SCHEMBL27526838 | 0.77 | RAB9A (0.50) | RAB9AL3MBTL1NPC1TSHRSMN1; SMN2 | |
| SCHEMBL28085964 | 0.77 | SMN1; SMN2 (0.58) | RAB9AL3MBTL1NPC1TSHRSMN1; SMN2 | |
| SCHEMBL3635988 | 0.77 | EGFR (0.62) | RAB9AL3MBTL1NPC1TSHRSMN1; SMN2 | |
| SCHEMBL1520184 | 0.75 | MAPT (0.62) | RAB9AL3MBTL1NPC1TSHRSMN1; SMN2 | |
| SCHEMBL9348953 | 0.74 | TSPO (0.45) | L3MBTL1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL3979754 | 0.74 | EGFR (0.69) | RAB9AL3MBTL1NPC1TSHRMEN1 | |
| SCHEMBL28607064 | 0.74 | RAB9A (0.49) | RAB9AL3MBTL1NPC1TSHRSMN1; SMN2 | |
| SCHEMBL22631290 | 0.74 | SMN1; SMN2 (0.48) | RAB9AL3MBTL1NPC1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707006-B1 | Aroyl-piperidine derivatives | NOVARTIS AG (CH) | 1999-04-07 | — | — | EP | disclosed |
| EP-0707006-A1 | Aroyl-piperidine derivatives | CIBA-GEIGY AG (CH) | 1996-04-17 | — | — | EP | disclosed |