Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL939536 | 0.90 | ALDH1A1 (0.64) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL998563 | 0.87 | ALDH1A1 (0.60) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL939537 | 0.87 | ALDH1A1 (0.60) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL2069896 | 0.87 | ALDH1A1 (0.60) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL13176601 | 0.86 | ALDH1A1 (0.59) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL27888658 | 0.86 | KMT2A (0.58) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL4221847 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL4221853 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL7213716 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL2170966 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736225-A | Continuous preparation method of dorterevir | 华东理工大学 | 2024-03-22 | — | — | CN | claimed |
| CN-108569949-A | A kind of synthesis 2- hydroxyls -2-（Containing methyl fluoride）The method of propionic acid | 北京艾德旺科技发展有限公司 | 2018-09-25 | — | — | CN | claimed |
| CN-101613280-A | Felodipine synthetic intermediate 2, the preparation method of 3-dichlorin benzylidene methyl acetoacetate | HEFEI LIFANG MEDICATION CO LTD | 2009-12-30 | — | — | CN | claimed |
| EP-0638552-B1 | PROCESS FOR SYNTHESIZING 4-SUBSTITUTED AZETIDINONE DERIVATIVE | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-06-04 | — | — | EP | claimed |
| EP-0672077-A1 | PROCESS FOR THE PRODUCTION OF POLYURETHANE FOAMS | EASTMAN CHEMICAL COMPANY (US) | 1995-09-20 | — | — | EP | claimed |
| WO-1994013725-A1 | PROCESS FOR THE PRODUCTION OF POLYURETHANE FOAMS | EASTMAN CHEMICAL COMPANY (US) | 1994-06-23 | — | — | WO | claimed |
| US-5234965-A | Acetoacetylation of some hydroxy groups of a polyhydric compound used to react with polyisocyanate in the presence of a blowing agent and catalyst to lower the viscosity | EASTMAN KODAK COMPANY (US) | 1993-08-10 | — | — | US | claimed |
| CN-122010885-A | Oraglycone intermediate, preparation method thereof and method for preparing key intermediate of Oraglycone | 江西同和药业股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-117736225-A | Continuous preparation method of dorterevir | 华东理工大学 | 2024-03-22 | — | — | CN | disclosed |
| EP-3644991-B1 | 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME LLC (US) | 2023-08-02 | — | — | EP | disclosed |
| US-11339156-B2 | 3-(1H-pyrazol-4-yl)pyridine allosteric modulators of the M4 muscarinic acetylcholine receptor | MERCK SHARP & DOHME CORP. (US) | 2022-05-24 | — | — | US | disclosed |
| US-11339156-B2 | 3-(1H-pyrazol-4-yl)pyridine allosteric modulators of the M4 muscarinic acetylcholine receptor | MERCK SHARP & DOHME CORP. (US) | 2022-05-24 | — | — | US | disclosed |
| US-20220023311-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES INC (US) | 2022-01-27 | — | — | US | disclosed |
| US-5113011-A | Acetoacetylation | EASTMAN KODAK COMPANY (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0448602-A1 | METHOD FOR FUNCTIONALIZATION OF NUCLEOPHILES | EASTMAN KODAK COMPANY (US) | 1991-10-02 | — | — | EP | disclosed |
| US-5051529-A | Transesterification, amidation and acetoacetylation of amines, alcohols, mercaptans and polymers | EASTMAN KODAK COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| WO-1991009959-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-HYDROXY-2-METHYLBUTYRATES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-11 | — | — | WO | disclosed |
| EP-0376859-A1 | Method for functionalization of nucleophiles | EASTMAN KODAK COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| WO-1990006911-A1 | METHOD FOR FUNCTIONALIZATION OF NUCLEOPHILES | EASTMAN KODAK COMPANY (US) | 1990-06-28 | — | — | WO | disclosed |
| EP-0227454-A2 | Crosslinked acetoacetic ester polymers | COOK PAINT AND VARNISH INC. (US) | 1987-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339156-B2 | 3-(1H-pyrazol-4-yl)pyridine allosteric modulators of the M4 muscarinic acetylcholine receptor | CHRM4, CHRM3, CHRM5 | ALDH1A1 2848/4885TDP1 1549/4885MAPK1 2916/4885 |
| US-20220023311-A1 | HEPATITIS B CORE PROTEIN MODULATORS | HAVCR2, FABP1, MAVS | ALDH1A1 3992/4885TDP1 4608/4885MAPK1 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.