Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | APEX1 | P27695 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3507581 | 0.85 | TLR9 (0.38) | LMNAKDM4ECYP3A4POLBCYP1A2 | |
| SCHEMBL18415133 | 0.83 | CYP1A2 (0.47) | PLGPLAUUGT2B7LMNAKDM4E | |
| SCHEMBL24633564 | 0.81 | CYP3A4 (0.36) | LMNAKDM4ECYP3A4POLBCYP1A2 | |
| SCHEMBL514592 | 0.75 | NOS3 (0.48) | PLGPLAUUGT2B7RECQLTDP1 | |
| SCHEMBL17198732 | 0.72 | UHRF1 (0.48) | PLGPLAUUGT2B7KMT2AMEN1 | |
| SCHEMBL19846691 | 0.72 | UHRF1 (0.48) | PLGPLAUUGT2B7KMT2AMEN1 | |
| SCHEMBL15277731 | 0.71 | PLG (0.41) | PLGPLAUUGT2B7RECQLTDP1 | |
| SCHEMBL21200276 | 0.71 | PLG (0.41) | PLGPLAUUGT2B7KDM4EKMT2A | |
| SCHEMBL22945803 | 0.71 | PLG (0.41) | PLGPLAUUGT2B7KMT2ACYP3A4 | |
| SCHEMBL568609 | 0.71 | PLG (0.41) | PLGPLAUUGT2B7KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563245-B | Substituted pyrrolidines and their use in medicine | 广东东阳光药业股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-113563245-A | Substituted pyrrolidine compounds and application thereof in medicines | 广东东阳光药业有限公司 | 2021-10-29 | — | — | CN | disclosed |