Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27840184 | 0.85 | FAAH (0.52) | FAAHPTGS2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5720398 | 0.84 | FAAH (0.56) | FAAHTSHRNSD3PTGS2MAPK13 | |
| SCHEMBL27934307 | 0.81 | FAAH (0.46) | FAAHACVR1ALDH1A1HTT | |
| SCHEMBL9425691 | 0.80 | FAAH (0.46) | FAAHTSHRNOX1 | |
| SCHEMBL8485057 | 0.80 | MAPK14 (0.70) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL27639359 | 0.80 | FAAH (0.56) | FAAHNSD3PTGS2MAPK13MAPK12 | |
| SCHEMBL27595420 | 0.80 | MAPK14 (0.59) | FAAHNSD3PTGS2MAPK13MAPK12 | |
| SCHEMBL28111191 | 0.80 | FAAH (0.53) | FAAHNSD3PTGS2LMNAALDH1A1 | |
| SCHEMBL27595419 | 0.79 | FAAH (0.67) | FAAHPTGS2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL27820755 | 0.77 | PTGS1 (0.46) | FAAHPTGS2MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073846-B | Diene/dienophile conjugates and with can re-workability compositions of thermosetting resin | 汉高知识产权控股有限责任公司 | 2019-04-16 | — | — | CN | disclosed |