Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720398 | 0.88 | FAAH (0.56) | FAAHPTGS2PTGS1LMNAMITF | |
| SCHEMBL27639359 | 0.83 | FAAH (0.56) | FAAHPTGS2PTGS1LMNAMITF | |
| SCHEMBL27595420 | 0.83 | MAPK14 (0.59) | FAAHPTGS2PTGS1LMNAGRM1 | |
| SCHEMBL6329705 | 0.80 | FAAH (0.53) | FAAHPTGS2PTGS1LMNAMITF | |
| SCHEMBL29290491 | 0.80 | FAAH (0.53) | FAAHPTGS2PTGS1LMNAMITF | |
| SCHEMBL27595419 | 0.80 | FAAH (0.67) | FAAHPTGS2PTGS1RAB9ALMNA | |
| SCHEMBL28237520 | 0.77 | FAAH (0.67) | FAAHPTGS2PTGS1RAB9ALMNA | |
| SCHEMBL14124512 | 0.76 | HTT (0.58) | FAAHPTGS2PTGS1LMNAGRM1 | |
| SCHEMBL28304784 | 0.75 | FAAH (0.53) | FAAHPTGS2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7201127 | 0.73 | FGFR1 (0.57) | FAAHPTGS2LMNAGAAMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106238098-A | The preparation method of a kind of 1,2,4,5 four substituted ramification of imidazole and catalyst for preparing thereof | 马鞍山市泰博化工科技有限公司 | 2016-12-21 | — | — | CN | disclosed |