Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256237 | 0.85 | CHRM2 (0.58) | CHRNB2CHRNA4CHRM2CHRM1CHRM3 | |
| SCHEMBL1422301 | 0.82 | TAAR1 (0.41) | — | |
| SCHEMBL27989272 | 0.81 | TAAR1 (0.39) | — | |
| SCHEMBL8510312 | 0.73 | KCNA5 (0.34) | — | |
| SCHEMBL27398929 | 0.72 | SLC6A4 (0.45) | SLC6A4HTR2CSLC6A2SLC6A3KCNH2 | |
| SCHEMBL14967219 | 0.72 | TAAR1 (0.37) | SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL12124793 | 0.70 | CHRM1 (0.48) | CHRM1SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL14966407 | 0.70 | TAAR1 (0.35) | — | |
| SCHEMBL20326088 | 0.70 | CYP19A1 (0.37) | SLC6A4HTR2CHTR2BHTR6 | |
| SCHEMBL13886623 | 0.70 | CHRNB2 (0.58) | CHRNB2CHRNA4CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641874-A | C for target protein degradation3The glutarimide degron body of carbon connection | C4医药公司 | 2019-04-16 | — | — | CN | disclosed |