Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL359506 | 0.85 | MERTK (0.48) | RAB9AALDH1A1NPC1SMN1; SMN2LMNA | |
| SCHEMBL28845219 | 0.76 | TLR8 (0.45) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL31661464 | 0.75 | FBP1 (0.44) | MAPTFBP1RAB9AHTTALDH1A1 | |
| SCHEMBL15877174 | 0.74 | ENPP1 (0.62) | MAPTFBP1RAB9AHTTALDH1A1 | |
| SCHEMBL24816160 | 0.74 | MAPT (0.50) | MAPTFBP1RAB9AHTTALDH1A1 | |
| SCHEMBL20116441 | 0.74 | MAPT (0.43) | MAPTRAB9AHTTALDH1A1NPC1 | |
| SCHEMBL10696793 | 0.74 | MERTK (0.58) | MAPTRAB9AHTTALDH1A1NPC1 | |
| SCHEMBL6370147 | 0.73 | LMNA (0.49) | MAPTRAB9AHTTALDH1A1NPC1 | |
| SCHEMBL8887345 | 0.73 | LMNA (0.49) | MAPTRAB9AHTTALDH1A1NPC1 | |
| SCHEMBL11835695 | 0.72 | MAPT (0.53) | MAPTRAB9AHTTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905234-B | A method of the synthesis chloro- 6- amino -7- ethoxyquinoline of linatinib intermediate 3- cyano -4- | 淮海工学院 | 2019-04-23 | — | — | CN | disclosed |
| CN-106905234-B | A method of the synthesis chloro- 6- amino -7- ethoxyquinoline of linatinib intermediate 3- cyano -4- | 淮海工学院 | 2019-04-23 | — | — | CN | disclosed |