SCHEMBL8860109

SCHEMBL8860109

CC(=O)Oc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.50
TDP1 Q9NUW8 2/20 0.50
CYP3A4 P08684 2/20 0.50
ALOX12 P18054 1/20 0.50
FABP3 P05413 1/20 0.46
TSHR P16473 4/20 0.44
ALDH1A1 P00352 2/20 0.44
RAB9A P51151 2/20 0.44
GAA P10253 2/20 0.44
CFD P00746 2/20 0.43
ESR1 P03372 1/20 0.41
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
HMGB1 P09429 1/20 0.41
HPGD P15428 1/20 0.41
GGT1 P19440 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
BLM P54132 1/20 0.41
NAPRT Q6XQN6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31612516 1.00 KDM4E (0.50) KDM4ETDP1CYP3A4ALOX12FABP3
SCHEMBL6137016 0.83 TSHR (0.53) KDM4ETDP1CYP3A4ALOX12TSHR
SCHEMBL30552290 0.83 FABP3 (0.49) KDM4ETDP1CYP3A4ALOX12FABP3
SCHEMBL121772 0.83 FABP3 (0.49) KDM4ETDP1CYP3A4ALOX12FABP3
SCHEMBL2929232 0.83 FABP3 (0.49) KDM4ETDP1CYP3A4ALOX12FABP3
SCHEMBL9775968 0.82 KDM4E (0.46) KDM4ETDP1CYP3A4ALOX12FABP3
SCHEMBL11057310 0.82 KDM4E (0.46) KDM4ETDP1CYP3A4ALOX12TSHR
SCHEMBL1153425 0.82 FABP3 (0.43) KDM4ETDP1CYP3A4ALOX12FABP3
SCHEMBL6691258 0.82 MAPK1 (0.49) KDM4ETDP1CYP3A4ALOX12TSHR
SCHEMBL31612517 0.82 MAPK1 (0.49) KDM4ETDP1CYP3A4ALOX12TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111257489-A Method for analyzing volatile phenolic compounds in water based on ultrasonic-assisted in-situ bubbling and simultaneous derivatization-dispersion liquid-liquid microextraction 浙江工业大学 2020-06-09 CN disclosed
WO-2017156354-A1 α-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2017-09-14 WO disclosed
WO-1997047200-A1 WIDE RANGE CLEANING AND DISINFECTING PREPARATIONS ABRAHAM WEITZMAN (CA) 1997-12-18 WO disclosed