Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29294222 | 0.87 | NLRP3 (0.53) | NLRP3MGLLKMT2AALDH1A1TSHR | |
| SCHEMBL29294799 | 0.84 | NLRP3 (0.43) | NLRP3MGLLKMT2ABACE1ALDH1A1 | |
| SCHEMBL29295193 | 0.84 | NLRP3 (0.44) | NLRP3KMT2ABACE1ALDH1A1TSHR | |
| SCHEMBL29294721 | 0.84 | NLRP3 (0.42) | NLRP3MGLLKMT2ABACE1ALDH1A1 | |
| SCHEMBL29295192 | 0.84 | NLRP3 (0.43) | NLRP3MGLLKMT2AALDH1A1TSHR | |
| SCHEMBL29294822 | 0.83 | NLRP3 (0.50) | NLRP3MGLLKMT2AALDH1A1MAPT | |
| SCHEMBL29295050 | 0.83 | NLRP3 (0.43) | NLRP3MGLLKMT2ABACE1ALDH1A1 | |
| SCHEMBL29295190 | 0.83 | NLRP3 (0.43) | NLRP3MGLLKMT2AALDH1A1MAPT | |
| SCHEMBL29294937 | 0.82 | NLRP3 (0.42) | NLRP3MGLLKMT2AALDH1A1TSHR | |
| SCHEMBL29295043 | 0.82 | NLRP3 (0.42) | NLRP3KMT2AALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |