Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29294961 | 0.90 | IRAK4 (0.40) | NLRP3KMT2AIRAK4TSHRALDH1A1 | |
| SCHEMBL29294222 | 0.85 | NLRP3 (0.53) | NLRP3KMT2AIRAK4TSHRALDH1A1 | |
| SCHEMBL29295050 | 0.84 | NLRP3 (0.43) | NLRP3KMT2AIRAK4TSHRALDH1A1 | |
| SCHEMBL29295193 | 0.83 | NLRP3 (0.44) | NLRP3KMT2ATSHRALDH1A1HSD17B10 | |
| SCHEMBL29294721 | 0.83 | NLRP3 (0.42) | NLRP3KMT2AIRAK4TSHRALDH1A1 | |
| SCHEMBL29295043 | 0.83 | NLRP3 (0.42) | NLRP3KMT2AIRAK4TSHRALDH1A1 | |
| SCHEMBL29295194 | 0.83 | NLRP3 (0.40) | NLRP3KMT2AIRAK4TSHRALDH1A1 | |
| SCHEMBL29294835 | 0.83 | NLRP3 (0.40) | NLRP3KMT2AIRAK4TSHRALDH1A1 | |
| SCHEMBL29294800 | 0.82 | NLRP3 (0.44) | NLRP3KMT2AIRAK4TSHRALDH1A1 | |
| SCHEMBL29294822 | 0.82 | NLRP3 (0.50) | NLRP3KMT2AIRAK4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |