Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29294585 | 0.88 | NLRP3 (0.51) | NLRP3MAPTMGLLHCAR1HTR3A | |
| SCHEMBL29294222 | 0.85 | NLRP3 (0.53) | NLRP3MGLLHCAR1ALDH1A1KDM4E | |
| SCHEMBL29294682 | 0.85 | NLRP3 (0.47) | NLRP3MAPTMGLLHCAR1HTR3A | |
| SCHEMBL29294631 | 0.85 | NLRP3 (0.47) | NLRP3MAPTMGLLRAB9A | |
| SCHEMBL29294647 | 0.85 | NLRP3 (0.48) | NLRP3MAPTMGLLHCAR1HTR3A | |
| SCHEMBL29294644 | 0.84 | NLRP3 (0.47) | NLRP3MAPTMGLLHCAR1HTR3A | |
| SCHEMBL29294641 | 0.84 | NLRP3 (0.47) | NLRP3MAPTMGLLHCAR1HTR3A | |
| SCHEMBL29294638 | 0.83 | NLRP3 (0.46) | NLRP3MAPTMGLLHCAR1HTR3A | |
| SCHEMBL29294818 | 0.83 | NLRP3 (0.45) | NLRP3MAPTMGLLHCAR1HTR3A | |
| SCHEMBL29294639 | 0.82 | NLRP3 (0.46) | NLRP3MAPTMGLLHCAR1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |