Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29294822 | 0.91 | NLRP3 (0.50) | NLRP3KDM4ETMIGD3RAB9ASMN1; SMN2 | |
| SCHEMBL29294222 | 0.91 | NLRP3 (0.53) | NLRP3KDM4ETMIGD3RAB9ASMN1; SMN2 | |
| SCHEMBL29294647 | 0.90 | NLRP3 (0.48) | NLRP3KDM4ETMIGD3RAB9ASMN1; SMN2 | |
| SCHEMBL29294529 | 0.89 | NLRP3 (0.43) | NLRP3KDM4ETMIGD3RAB9ASMN1; SMN2 | |
| SCHEMBL29294644 | 0.89 | NLRP3 (0.47) | NLRP3KDM4ETMIGD3RAB9ASMN1; SMN2 | |
| SCHEMBL29294631 | 0.88 | NLRP3 (0.47) | NLRP3RAB9AMGLLMAPT | |
| SCHEMBL29294682 | 0.88 | NLRP3 (0.47) | NLRP3KDM4ETMIGD3RAB9ASMN1; SMN2 | |
| SCHEMBL29294833 | 0.88 | NLRP3 (0.47) | NLRP3KDM4ERAB9ASMN1; SMN2HCAR1 | |
| SCHEMBL29294695 | 0.87 | HRH4 (0.47) | NLRP3KDM4ETMIGD3RAB9ASMN1; SMN2 | |
| SCHEMBL29294641 | 0.87 | NLRP3 (0.47) | NLRP3KDM4ETMIGD3RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |