Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29294065 | 0.96 | NLRP3 (0.53) | NLRP3TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL29295109 | 0.94 | NLRP3 (0.52) | NLRP3TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL29295246 | 0.91 | NLRP3 (0.51) | NLRP3SMN1; SMN2KDM4ETMIGD3RAB9A | |
| SCHEMBL29295145 | 0.91 | NLRP3 (0.51) | NLRP3SMN1; SMN2KDM4ETMIGD3RAB9A | |
| SCHEMBL29294068 | 0.90 | NLRP3 (0.47) | NLRP3TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL29294075 | 0.90 | NLRP3 (0.49) | NLRP3TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL29294708 | 0.89 | NLRP3 (0.54) | NLRP3TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL29294829 | 0.88 | NLRP3 (0.65) | NLRP3TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL29294901 | 0.88 | NLRP3 (0.45) | NLRP3TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL29295245 | 0.85 | NLRP3 (0.54) | NLRP3TSHRALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |