Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29294065 | 0.93 | NLRP3 (0.53) | NLRP3KMT2ATSHRMEN1HSD17B10 | |
| SCHEMBL29295243 | 0.90 | NLRP3 (0.50) | NLRP3KMT2ATSHRMEN1HSD17B10 | |
| SCHEMBL29295109 | 0.90 | NLRP3 (0.52) | NLRP3KMT2ATSHRMEN1HSD17B10 | |
| SCHEMBL29294068 | 0.89 | NLRP3 (0.47) | NLRP3KMT2ATSHRMEN1HSD17B10 | |
| SCHEMBL29294901 | 0.89 | NLRP3 (0.45) | NLRP3KMT2ATSHRMEN1HSD17B10 | |
| SCHEMBL29295115 | 0.88 | NLRP3 (0.40) | NLRP3KMT2ATSHRMEN1HSD17B10 | |
| SCHEMBL29294073 | 0.86 | NLRP3 (0.64) | NLRP3KMT2ATSHRMEN1HSD17B10 | |
| SCHEMBL29295145 | 0.85 | NLRP3 (0.51) | NLRP3TNKSTNKS2SMN1; SMN2MGLL | |
| SCHEMBL29295246 | 0.85 | NLRP3 (0.51) | NLRP3TNKSTNKS2SMN1; SMN2MGLL | |
| SCHEMBL29295046 | 0.83 | NLRP3 (0.42) | NLRP3KMT2ATSHRMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397663-A1 | 6-AMINOPYRAZOLOPYRIMIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2024-07-10 | — | — | EP | disclosed |