Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10306614 | 0.89 | S1PR1 (0.42) | S1PR1ADRA1DCHKAHDAC3HDAC8 | |
| SCHEMBL2014463 | 0.78 | S1PR1 (0.42) | S1PR1ADRA1DCHKAHDAC3HDAC8 | |
| SCHEMBL2014460 | 0.78 | S1PR1 (0.42) | S1PR1ADRA1DCHKAHDAC3HDAC8 | |
| SCHEMBL23771214 | 0.78 | ALDH1A1 (0.47) | CHKAHDAC3HDAC8L3MBTL1NCF1 | |
| SCHEMBL2014436 | 0.77 | S1PR1 (0.39) | S1PR1ADRA1DL3MBTL3L3MBTL1SPHK1 | |
| SCHEMBL17929332 | 0.72 | HDAC3 (0.34) | HDAC3HDAC8 | |
| SCHEMBL17553360 | 0.71 | KMT2A (0.45) | — | |
| SCHEMBL12127177 | 0.69 | ADRA1D (0.40) | ADRA1DCHKAL3MBTL1 | |
| SCHEMBL8353735 | 0.67 | CHKA (0.57) | S1PR1CHKAHDAC3HDAC8L3MBTL1 | |
| SCHEMBL20799635 | 0.66 | MEN1 (0.40) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3621958-B1 | PHOTOCHROMIC INDENO FUSED PHENANTHRENOPYRAN COMPOUNDS | TRANSITIONS OPTICAL LTD (IE) | 2024-07-10 | — | — | EP | disclosed |