Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PGK1 | P00558 | 2/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29295389 | 0.88 | ACHE (0.62) | ACHELMNACYP3A4CYP1A2CYP2D6 | |
| Bazinaprine SCHEMBL499295 | 0.88 | ACHE (1.00) | ACHELMNACYP3A4CYP1A2CYP2D6 | |
| Bazinaprine SCHEMBL10830678 | 0.87 | ACHE (0.98) | ACHELMNACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL29295396 | 0.84 | ACHE (0.65) | ACHELMNACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL31759026 | 0.83 | ACHE (0.82) | ACHELMNACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL29295393 | 0.83 | ACHE (0.56) | ACHELMNACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL1753124 | 0.78 | ACHE (0.62) | ACHELMNACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL29295388 | 0.76 | ACHE (0.54) | ACHELMNACYP3A4CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL10830590 | 0.75 | ACHE (0.70) | ACHELMNACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL12691782 | 0.75 | ACHE (0.58) | ACHELMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148148-A1 | PYRIDAZINE BASED SMALL MOLECULE INHIBITOR OF COGNITIVE IMPAIRMENT | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-07-11 | — | — | WO | disclosed |