Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29295388 | 0.90 | ACHE (0.54) | ACHECYP3A4LMNACYP1A2CYP2D6 | |
| SCHEMBL31759026 | 0.89 | ACHE (0.82) | ACHECYP3A4LMNACYP1A2CYP2D6 | |
| SCHEMBL29295392 | 0.86 | ACHE (0.50) | ACHECYP3A4LMNACYP1A2CYP2D6 | |
| SCHEMBL1752978 | 0.86 | LMNA (0.80) | ACHECYP3A4LMNACYP1A2CYP2D6 | |
| SCHEMBL29295397 | 0.84 | ACHE (0.78) | ACHECYP3A4LMNACYP1A2CYP2D6 | |
| SCHEMBL29295390 | 0.82 | CSNK1D (0.51) | ACHECYP3A4LMNACYP1A2CYP2D6 | |
| SCHEMBL1752932 | 0.81 | LMNA (0.72) | ACHECYP3A4LMNACYP1A2CYP2D6 | |
| SCHEMBL16853222 | 0.80 | ACHE (0.73) | ACHECYP3A4LMNACYP1A2CYP2D6 | |
| SCHEMBL29295394 | 0.79 | KAT2B (0.44) | ACHECYP3A4LMNACYP1A2CYP2D6 | |
| SCHEMBL1752900 | 0.79 | ACHE (1.00) | ACHECYP3A4LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148148-A1 | PYRIDAZINE BASED SMALL MOLECULE INHIBITOR OF COGNITIVE IMPAIRMENT | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-07-11 | — | — | WO | disclosed |