Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | SELP | P16109 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12324725 | 0.83 | PLA2G2C (0.45) | FOLH1PLA2G10PLA2G2CCTSK | |
| SCHEMBL12295313 | 0.81 | GLP1R (0.59) | GLP1RPLA2G10PLA2G2CMEN1KMT2A | |
| SCHEMBL12295886 | 0.81 | GLP1R (0.59) | GLP1RPLA2G10PLA2G2CMEN1KMT2A | |
| SCHEMBL12296713 | 0.81 | GLP1R (0.59) | GLP1RPLA2G10PLA2G2CMEN1KMT2A | |
| SCHEMBL16478853 | 0.81 | GLP1R (0.45) | GLP1RPLA2G10PLA2G2C | |
| SCHEMBL12296113 | 0.80 | GLP1R (0.58) | GLP1RPLA2G10PLA2G2C | |
| SCHEMBL30063936 | 0.80 | CASP2 (0.44) | GLP1RCASP2MEN1KMT2A | |
| SCHEMBL30940194 | 0.80 | CASP2 (0.47) | GLP1RCASP2MEN1KMT2A | |
| SCHEMBL29832716 | 0.80 | CASP2 (0.47) | GLP1RCASP2MEN1KMT2A | |
| SCHEMBL24798437 | 0.79 | FOLH1 (0.33) | FOLH1SELPPLA2G2CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883926-B1 | BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDE DERIVATIVES AND PROTEIN CONJUGATES THEREOF FOR USE AS LXR AGONISTS | REGENERON PHARMA (US) | 2024-07-10 | — | — | EP | disclosed |