Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1564708 | 0.85 | LMNA (0.46) | LMNAHRH4HRH3SLC6A2DRD1 | |
| SCHEMBL15419089 | 0.85 | LMNA (0.46) | LMNAHRH4HRH3SLC6A2DRD1 | |
| SCHEMBL18535611 | 0.85 | LMNA (0.46) | LMNAHRH4HRH3SLC6A2DRD1 | |
| SCHEMBL1566210 | 0.85 | LMNA (0.46) | LMNAHRH4HRH3SLC6A2DRD1 | |
| SCHEMBL29295667 | 0.84 | LMNA (0.47) | LMNAHRH4HRH3BCHEACHE | |
| SCHEMBL3031655 | 0.83 | SLC6A2 (0.55) | LMNAHRH4HRH3BCHEACHE | |
| SCHEMBL971425 | 0.83 | SLC6A2 (0.55) | LMNAHRH4HRH3BCHEACHE | |
| SCHEMBL971427 | 0.83 | SLC6A2 (0.55) | LMNAHRH4HRH3BCHEACHE | |
| SCHEMBL10420228 | 0.82 | LMNA (0.54) | LMNAHRH4HRH3BCHEACHE | |
| SCHEMBL19559233 | 0.82 | LMNA (0.54) | LMNAHRH4HRH3BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148308-A1 | NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED (US) | 2024-07-11 | — | — | WO | disclosed |