Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1564320 | 0.85 | LMNA (0.44) | LMNAHRH4HRH3CTSLCTSB | |
| SCHEMBL1565954 | 0.85 | LMNA (0.44) | LMNAHRH4HRH3CTSLCTSB | |
| SCHEMBL16138311 | 0.83 | MGLL (0.49) | LMNAMGLL | |
| SCHEMBL16138316 | 0.83 | MGLL (0.49) | LMNAMGLL | |
| SCHEMBL16138331 | 0.83 | MGLL (0.49) | LMNAMGLL | |
| SCHEMBL19559233 | 0.83 | LMNA (0.54) | LMNAHRH4HRH3CTSLCTSB | |
| SCHEMBL10420228 | 0.83 | LMNA (0.54) | LMNAHRH4HRH3CTSLCTSB | |
| SCHEMBL5660476 | 0.82 | LMNA (0.50) | LMNAHRH4HRH3CYP1A2 | |
| SCHEMBL21283683 | 0.82 | LMNA (0.50) | LMNAHRH4HRH3CYP1A2 | |
| SCHEMBL25306201 | 0.79 | LMNA (0.45) | LMNAHRH4HRH3CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148308-A1 | NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED (US) | 2024-07-11 | — | — | WO | disclosed |