SCHEMBL292964

SCHEMBL292964

O=C(O)C=Cc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.67
HDAC3 O15379 2/20 0.67
HDAC4 P56524 2/20 0.67
HDAC1 Q13547 2/20 0.67
HDAC2 Q92769 2/20 0.67
HDAC8 Q9BY41 2/20 0.67
HDAC6 Q9UBN7 2/20 0.67
TNKS O95271 1/20 0.67
HDAC7 Q8WUI4 1/20 0.67
HDAC10 Q969S8 1/20 0.67
HDAC11 Q96DB2 1/20 0.67
TNKS2 Q9H2K2 1/20 0.67
HDAC9 Q9UKV0 1/20 0.67
HDAC5 Q9UQL6 1/20 0.67
FFAR1 O14842 2/20 0.58
PKM P14618 2/20 0.57
CA12 O43570 1/20 0.57
AKR1B10 O60218 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL292963 1.00 HCAR2 (0.67) HCAR2HDAC3HDAC4HDAC1HDAC2
Cinnamic Acid SCHEMBL9718485 0.86 HDAC3 (0.63) HCAR2HDAC3HDAC4HDAC1HDAC2
SCHEMBL8195098 0.85 HDAC1 (0.62) HCAR2HDAC3HDAC4HDAC1HDAC2
SCHEMBL28181231 0.85 HCAR2 (0.53) HCAR2HDAC3HDAC4HDAC1HDAC2
SCHEMBL8195099 0.85 HDAC1 (0.62) HCAR2HDAC3HDAC4HDAC1HDAC2
Diphenylamine SCHEMBL29876118 0.83 HSD17B10 (0.60) HCAR2HDAC3HDAC4HDAC1HDAC2
Diphenylamine SCHEMBL21145064 0.83 HSD17B10 (0.60) HCAR2HDAC3HDAC4HDAC1HDAC2
Diphenylamine SCHEMBL21145065 0.83 HSD17B10 (0.60) HCAR2HDAC3HDAC4HDAC1HDAC2
SCHEMBL292363 0.82 CA12 (0.62) CA12CA1CA2TYRCA7
SCHEMBL292364 0.82 CA12 (0.62) CA12CA1CA2TYRCA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
WO-2020054484-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT 株式会社ブリヂストン 2020-03-19 WO disclosed
US-20180244808-A1 METHOD FOR PRODUCING MODIFIED DIENE-BASED RUBBER, RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2018-08-30 US disclosed
EP-3345933-A1 METHOD FOR PRODUCING MODIFIED DIENE RUBBER, RUBBER COMPOSITION, AND TIRE Bridgestone Corporation (JP) 2018-07-11 EP disclosed
EP-2845869-B1 MODIFIED NATURAL RUBBER, METHOD FOR PRODUCING SAME, RUBBER COMPOSITION, AND TIRE BRIDGESTONE CORP (JP) 2018-01-17 EP disclosed
US-9428619-B2 Interpolymers containing isobutylene and diene mer units BRIDGESTONE CORPORATION (JP) 2016-08-30 US disclosed
US-9181378-B2 Modified natural rubber and method of manufacturing the same, rubber composition and tire BRIDGESTONE CORPORATION (JP) 2015-11-10 US disclosed
US-9132697-B2 Modified natural rubber or modified natural rubber latex, and rubber composition and pneumatic tire BRIDGESTONE CORPORATION (JP) 2015-09-15 US disclosed
EP-2845869-A1 MODIFIED NATURAL RUBBER, METHOD FOR PRODUCING SAME, RUBBER COMPOSITION, AND TIRE Bridgestone Corporation (JP) 2015-03-11 EP disclosed
US-8960247-B2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed
EP-1500679-A1 DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2005-01-26 EP disclosed
WO-2004106397-A1 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2004-12-09 WO disclosed
US-6740704-B2 UNIFORM DISPERSION JSR CORPORATION (JP) 2004-05-25 US disclosed
US-20040030027-A1 Diene rubber/inorganic compound composite and method for producing the same and rubber composition BRIDGESTONE CORPORATION (JP) 2004-02-12 US disclosed
EP-1323775-A1 DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND METHOD FOR PRODUCING THE SAME AND RUBBER COMPOSITION JSR Corporation (JP) 2003-07-02 EP disclosed
US-20020111418-A1 Methods for producing diene-based rubber/inorganic compound complexes and rubber compositions containing the same JSR CORPORATION (JP) 2002-08-15 US disclosed
EP-1215226-A2 Diene-based rubber/inorganic compound complexes, methods for producing the same and rubber compositions containing the same JSR Corporation (JP) 2002-06-19 EP disclosed
US-4147880-A Age resisters and age resistant polymeric compositions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-04-03 US disclosed
US-3966801-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1976-06-29 US disclosed
US-3953411-A Age resistant polymers of 4-(arylamino)aryl esters of α,β unsaturated carboxylic acids THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-04-27 US disclosed