SCHEMBL2929862

SCHEMBL2929862

C[N+](C)(CCCCCC[N+](C)(C)C1CC(C(N)=O)N(c2ccc(N)cc2)C1)C1CC(C(N)=O)N(c2ccc(N)cc2)C1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SYK P43405 2/20 0.34
GRM2 Q14416 1/20 0.32
GFER P55789 2/20 0.31
CASP6 P55212 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6503630 0.99 SYK (0.33) SYKGRM2GFERCASP6
SCHEMBL6603619 0.84 CASP6 (0.35) SYKGFERCASP6
Hydrochloric Acid SCHEMBL6095993 0.83 CASP6 (0.34) SYKGFERCASP6
SCHEMBL2926121 0.80 GRM2 (0.31) GRM2GFER
Hydrochloric Acid SCHEMBL6503157 0.79 GRM2 (0.30) GRM2GFER
SCHEMBL6386872 0.73 SYK (0.47) SYKGRM2GFERCASP6
SCHEMBL6386185 0.73 SYK (0.35) SYKGFERCASP6
Hydrochloric Acid SCHEMBL6097451 0.72
SCHEMBL2929100 0.69 MAPT (0.40) GRM2GFERCASP6
Hydrochloric Acid SCHEMBL6494082 0.68 MAPT (0.39) GRM2GFERCASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1396486-A1 Bis-paraphenylendiamine derivatives comprising pyrrolidine groups and their use for the colouration of keratinic fibres L'OREAL (FR) 2004-03-10 EP claimed
EP-1728500-B1 Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye OREAL (FR) 2010-01-27 EP disclosed
EP-1728500-A1 Composition for dyeing keratinic fibres comprising a diamino-N,N-dihydro-pyrazolon derivative and a cationic oxidation dye L'OREAL (FR) 2006-12-06 EP disclosed
EP-1396486-A1 Bis-paraphenylendiamine derivatives comprising pyrrolidine groups and their use for the colouration of keratinic fibres L'OREAL (FR) 2004-03-10 EP disclosed