Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 7/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 7/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 7/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2826588 | 0.94 | GRIN2D (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL2832554 | 0.92 | GRIN2D (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6105432 | 0.92 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL26786777 | 0.89 | EPHX2 (0.41) | SMN1; SMN2 | |
| SCHEMBL14466783 | 0.89 | EPHX2 (0.41) | SMN1; SMN2 | |
| SCHEMBL2927873 | 0.87 | EPHX2 (0.43) | TSHRTHRB | |
| SCHEMBL2921447 | 0.87 | EPHX2 (0.43) | TSHRTHRB | |
| SCHEMBL128692 | 0.85 | EPHX2 (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL20077560 | 0.85 | EPHX2 (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL20067101 | 0.85 | EPHX2 (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348356-A1 | BUTYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION | EVONIK OPERATIONS GMBH (DE) | 2023-11-02 | — | — | US | disclosed |
| US-20210276939-A1 | BUTYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION | EVONIK OPERATIONS GMBH (DE) | 2021-09-09 | — | — | US | disclosed |
| EP-3121180-B1 | BUTYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION | EVONIK DEGUSSA GMBH (DE) | 2018-09-12 | — | — | EP | disclosed |
| US-20170022138-A1 | BUTYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION | EVONIK DEGUSSA GMBH (DE) | 2017-01-26 | — | — | US | disclosed |
| EP-3121180-A2 | BUTYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION | Evonik Degussa GmbH (DE) | 2017-01-25 | — | — | EP | disclosed |
| US-20150231121-A1 | POSITIVE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTOR | H. LUNDBECK A/S (DK) | 2015-08-20 | — | — | US | disclosed |
| EP-1303525-B1 | PRODUCTION OF NOVEL PHOSPHANE LIGANDS AND USE IN CATALYTICAL REACTIONS | EVONIK DEGUSSA GMBH (DE) | 2010-09-08 | — | — | EP | disclosed |
| US-7148176-B2 | Production of novel phosphane ligands and use in catalytical reactions | DEGUSSA AG (DE) | 2006-12-12 | — | — | US | disclosed |
| US-20040068131-A1 | (adamantyl)nP(alkyl)m(1a); (adamantyl)o(Alkyl)qP (alkylene')P(adamantyl)r(alkyl)s , wherein adamantyl bonded to phosphorus atom in position 1, or 2, useful for refining halogenoaromatics | EVONIK DEGUSSA GMBH (DE) | 2004-04-08 | — | — | US | disclosed |
| EP-1303525-A1 | PRODUCTION OF NOVEL PHOSPHANE LIGANDS AND USE IN CATALYTICAL REACTIONS | Degussa AG (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002010178-A1 | ADAMANTYL GROUPS CONTAINING PHOSPHANE LIGANDS, THE PRODUCTION AND USE THEREOF IN CATALYTICAL REACTIONS | DEGUSSA AG (DE) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348356-A1 | BUTYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION | C3AR1, CBR3, C1R | GRIN2D 2441/4885GRIN3B 1501/4885GRIN1 1952/4885 |
| US-20040068131-A1 | (adamantyl)nP(alkyl)m(1a); (adamantyl)o(Alkyl)qP (alkylene')P(adamantyl)r(alkyl)s , wherein adamantyl bonded to phosphorus atom in position 1, or 2, useful for refining halogenoaromatics | NAPEPLD, NAPA, APBA1 | GRIN2D 1630/4885GRIN3B 2849/4885GRIN1 1180/4885 |
| US-20150231121-A1 | POSITIVE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTOR | CHRNG, CHRNA7, CHRNA2 | GRIN2D 401/4885GRIN3B 49/4885GRIN1 48/4885 |
| US-20210276939-A1 | BUTYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION | C3AR1, CBR3, C1R | GRIN2D 2441/4885GRIN3B 1501/4885GRIN1 1952/4885 |
| US-20170022138-A1 | BUTYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION | C3AR1, CBR3, C1R | GRIN2D 2461/4885GRIN3B 1508/4885GRIN1 1975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.