Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926808 | 0.81 | NTRK1 (0.38) | NTRK1MAPTL3MBTL1NPSR1NTRK3 | |
| SCHEMBL27324019 | 0.78 | MAPT (0.54) | NTRK1MAPTL3MBTL1NPSR1NTRK3 | |
| SCHEMBL10205892 | 0.70 | NTRK1 (0.58) | NTRK1MAPTL3MBTL1NPSR1NTRK3 | |
| SCHEMBL29894085 | 0.69 | ADORA2A (0.67) | AKT1ADORA1FGFR1GSK3BCLK4 | |
| SCHEMBL2926500 | 0.69 | DYRK1A (0.47) | AKT1AKT2ADORA1DYRK1AADORA2A | |
| SCHEMBL1384932 | 0.68 | ADORA2A (0.45) | NTRK1L3MBTL1NPSR1AKT1AKT2 | |
| SCHEMBL2965992 | 0.66 | NTRK1 (0.39) | NTRK1ADORA1GSK3BADORA2A | |
| SCHEMBL2611837 | 0.65 | MAPT (0.57) | NTRK1MAPTL3MBTL1NPSR1NTRK3 | |
| SCHEMBL28841969 | 0.62 | NTRK1 (0.54) | NTRK1MAPTL3MBTL1NPSR1NTRK3 | |
| SCHEMBL3181459 | 0.62 | PDK2 (0.38) | MAPTL3MBTL1HTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611131-B1 | PYRAZOLOPYRIDINE DERIVATES | PALAU PHARMA SA (ES) | 2010-09-15 | — | — | EP | claimed |