Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 13/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 10/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | FRK | P42685 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2929315 | 0.84 | CSNK1D (0.37) | NTRK1CSNK1DCSNK1EMAPK14MAPK11 | |
| SCHEMBL2926320 | 0.75 | MAPK14 (0.64) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 | |
| SCHEMBL1384759 | 0.73 | CSNK1D (0.51) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 | |
| SCHEMBL2927863 | 0.71 | DYRK1A (0.41) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 | |
| SCHEMBL1384219 | 0.70 | MAPK14 (0.48) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 | |
| SCHEMBL1384763 | 0.69 | MAP4K4 (0.42) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 | |
| SCHEMBL2932162 | 0.68 | MAPK14 (0.35) | NTRK1CSNK1DCSNK1EMAPK14MAP4K4 | |
| SCHEMBL1386511 | 0.67 | BRAF (0.46) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 | |
| SCHEMBL29652643 | 0.67 | MAPK14 (0.47) | CSNK1DCSNK1EMAPK14MAPK11MAPK13 | |
| SCHEMBL2929949 | 0.66 | NTRK1 (0.41) | NTRK1ADORA2AADORA1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611131-B1 | PYRAZOLOPYRIDINE DERIVATES | PALAU PHARMA SA (ES) | 2010-09-15 | — | — | EP | disclosed |