SCHEMBL29300488

SCHEMBL29300488

CC(C)CCCCNC(=O)[C@H](N)CCCCNC(=O)c1ccc(CNCN2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)cc1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 12/20 0.50
LMNA P02545 2/20 0.42
MAPK11 Q15759 1/20 0.42
MAPK14 Q16539 1/20 0.42
TERT O14746 2/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ITGB3 P05106 2/20 0.38
ITGA2B P08514 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29300535 0.93 FOLH1 (0.50) FOLH1LMNA
SCHEMBL29299818 0.90 FOLH1 (0.62) FOLH1LMNAMAPK11MAPK14HTT
SCHEMBL29300499 0.84 DPP7 (0.44) FOLH1SMN1; SMN2
SCHEMBL29300554 0.83 LMNA (0.52) FOLH1LMNAALDH1A1GAAMAPT
SCHEMBL29299810 0.82 FOLH1 (0.70) FOLH1LMNAMAPK11MAPK14HTT
SCHEMBL29300491 0.80 FOLH1 (0.46) FOLH1
SCHEMBL29299859 0.79 TERT (0.47) MAPK11MAPK14TERTSMN1; SMN2ITGB3
SCHEMBL29300167 0.79 TERT (0.47) MAPK11MAPK14TERTSMN1; SMN2ITGB3
SCHEMBL29300382 0.77 TERT (0.52) MAPK11MAPK14TERTSMN1; SMN2ITGB3
SCHEMBL29299797 0.77 DPP7 (0.46) FOLH1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R FOLH1 335/4885LMNA 3809/4885MAPK11 1574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.