Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | TTPA | P49638 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PNLIP | P16233 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | IDE | P14735 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2635649 | 0.92 | LMNA (0.43) | MAPTLMNAKMT2AMEN1GSTP1 | |
| SCHEMBL21929591 | 0.77 | LMNA (0.55) | MAPTLMNAKMT2AMEN1GSTP1 | |
| SCHEMBL21931412 | 0.77 | LMNA (0.55) | MAPTLMNAKMT2AMEN1GSTP1 | |
| SCHEMBL21131789 | 0.77 | LMNA (0.55) | MAPTLMNAKMT2AMEN1GSTP1 | |
| SCHEMBL9285268 | 0.77 | LMNA (0.55) | MAPTLMNAKMT2AMEN1GSTP1 | |
| SCHEMBL21929589 | 0.77 | LMNA (0.55) | MAPTLMNAKMT2AMEN1GSTP1 | |
| SCHEMBL21931411 | 0.77 | LMNA (0.55) | MAPTLMNAKMT2AMEN1GSTP1 | |
| SCHEMBL29305286 | 0.76 | LMNA (0.62) | MAPTLMNAKMT2AMEN1GSTP1 | |
| SCHEMBL21754694 | 0.71 | LMNA (0.48) | MAPTLMNAKMT2AMEN1GSTP1 | |
| SCHEMBL20646344 | 0.71 | LMNA (0.48) | MAPTLMNAKMT2AMEN1GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228454-A1 | RING CLOSURE OF BENZOQUINONES CONTAINING AN UNSATURATED SIDE CHAIN USING A BASE IN TWO-PHASE SYSTEM | DSM IP ASSETS B.V. (NL) | 2024-07-11 | — | — | US | disclosed |
| US-20240228454-A1 | RING CLOSURE OF BENZOQUINONES CONTAINING AN UNSATURATED SIDE CHAIN USING A BASE IN TWO-PHASE SYSTEM | DSM IP ASSETS B.V. (NL) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228454-A1 | RING CLOSURE OF BENZOQUINONES CONTAINING AN UNSATURATED SIDE CHAIN USING A BASE IN TWO-PHASE SYSTEM | TTPA, SQLE, VKORC1 | MAPT 4362/4885LMNA 770/4885KMT2A 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.