Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270476 | 0.78 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3ALDH1A1KDM4C | |
| SCHEMBL2163156 | 0.71 | ALDH1A1 (0.53) | ALDH1A1KDM4CMEN1KMT2AMMP2 | |
| SCHEMBL7003557 | 0.71 | ALDH1A1 (0.53) | ALDH1A1KDM4CMEN1CYP2C9CYP2C19 | |
| SCHEMBL8952292 | 0.70 | BCHE (0.43) | ALDH1A1MMP2MMP13PPARGMAPT | |
| Hydrochloric Acid SCHEMBL15794639 | 0.69 | SLC6A4 (0.97) | SLC6A2SLC6A4SLC6A3IDO1 | |
| SCHEMBL11816671 | 0.68 | ALDH1A1 (0.50) | ALDH1A1KDM4CMMP2MAPTLMNA | |
| SCHEMBL17358739 | 0.66 | ALDH1A1 (0.51) | SLC6A2SLC6A4SLC6A3ALDH1A1KDM4C | |
| SCHEMBL5836429 | 0.66 | ALDH1A1 (0.48) | ALDH1A1MMP2MMP13PPARGMAPT | |
| SCHEMBL790660 | 0.65 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3ALDH1A1SLC1A3 | |
| SCHEMBL8417301 | 0.65 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060985-A9 | COMPOSITIONS, METHODS AND KITS RELATING TO URIDINE PHOSPHORYLASE GENE MUTATIONS | UNIV YALE (US) | 2002-10-31 | — | — | WO | claimed |
| WO-2001060985-A2 | COMPOSITIONS, METHODS AND KITS RELATING TO URIDINE PHOSPHORYLASE GENE MUTATIONS | YALE UNIVERSITY (US) | 2001-08-23 | — | — | WO | claimed |
| EP-1651674-B1 | UPS AS MODIFIERS OF THE BETA CATENIN PATHWAY AND METHODS OF USE | EXELIXIS INC (US) | 2010-09-29 | — | — | EP | disclosed |
| US-20060037088-A1 | Gene expression levels as predictors of chemoradiation response of cancer | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2006-02-16 | — | — | US | disclosed |
| WO-2001060985-A9 | COMPOSITIONS, METHODS AND KITS RELATING TO URIDINE PHOSPHORYLASE GENE MUTATIONS | UNIV YALE (US) | 2002-10-31 | — | — | WO | disclosed |
| WO-2001060985-A2 | COMPOSITIONS, METHODS AND KITS RELATING TO URIDINE PHOSPHORYLASE GENE MUTATIONS | YALE UNIVERSITY (US) | 2001-08-23 | — | — | WO | disclosed |