Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26445138 | 0.82 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1KDM4ENPC1BDKRB1 | |
| SCHEMBL26445170 | 0.82 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1KDM4ENPC1BDKRB1 | |
| SCHEMBL26700710 | 0.81 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1KDM4ENPC1BDKRB1 | |
| SCHEMBL26707719 | 0.79 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1KDM4ENPC1BDKRB1 | |
| SCHEMBL26700713 | 0.74 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1KDM4ENPC1BDKRB1 | |
| SCHEMBL22849630 | 0.73 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1KDM4ENPC1HRH3 | |
| SCHEMBL17212824 | 0.73 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1KDM4ENPC1HRH3 | |
| SCHEMBL23730021 | 0.73 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1KDM4ENPC1HRH3 | |
| SCHEMBL26376818 | 0.73 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1KDM4ENPC1BDKRB1 | |
| SCHEMBL20413347 | 0.72 | KDM4E (0.51) | L3MBTL1ALDH1A1KDM4ENPC1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148060-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |