Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22463774 | 0.83 | SIGMAR1 (0.52) | KDM1ADRD1PDK1EBPSIGMAR1 | |
| SCHEMBL14027741 | 0.83 | SIGMAR1 (0.52) | KDM1ADRD1PDK1EBPSIGMAR1 | |
| SCHEMBL29645051 | 0.83 | SIGMAR1 (0.52) | KDM1ADRD1PDK1EBPSIGMAR1 | |
| SCHEMBL6043570 | 0.81 | KDM1A (0.44) | KDM1ADRD1PDK1EBPSIGMAR1 | |
| SCHEMBL6043208 | 0.81 | KDM1A (0.44) | KDM1ADRD1PDK1EBPSIGMAR1 | |
| SCHEMBL26894002 | 0.81 | KDM1A (0.44) | KDM1ADRD1PDK1EBPSIGMAR1 | |
| SCHEMBL4024791 | 0.81 | KDM1A (0.44) | KDM1ADRD1PDK1EBPSIGMAR1 | |
| SCHEMBL22463763 | 0.81 | EBP (0.59) | KDM1ADRD1PDK1EBPSIGMAR1 | |
| SCHEMBL9801679 | 0.81 | KEAP1 (0.52) | KDM1ADRD1PDK1EBPSIGMAR1 | |
| SCHEMBL26621721 | 0.81 | KDM1A (0.44) | KDM1ADRD1PDK1EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148060-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |