Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997588 | 0.77 | GAA (0.46) | GAAMEN1KMT2ABIRC2ALDH1A1 | |
| SCHEMBL3450464 | 0.76 | ALDH1A1 (0.44) | GAAMEN1KMT2ABIRC2ALDH1A1 | |
| SCHEMBL1008007 | 0.76 | KDM4E (0.42) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1007467 | 0.76 | KDM4E (0.42) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1006794 | 0.76 | KDM4E (0.42) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL26089493 | 0.76 | HSD17B10 (0.38) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL29307370 | 0.76 | HSD17B10 (0.38) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL12226502 | 0.75 | HRH2 (0.37) | MEN1KMT2ABIRC2ALDH1A1LMNA | |
| SCHEMBL14115761 | 0.75 | GAA (0.68) | GAAKMT2ABIRC2ALDH1A1LMNA | |
| SCHEMBL12226495 | 0.75 | HRH2 (0.37) | MEN1KMT2ABIRC2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148029-A2 | ORGANIC COMPOUNDS AS NLRP3 INHIBITORS | KODIAK SCIENCES INC. (US) | 2024-07-11 | — | — | WO | disclosed |