Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 4/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12632547 | 0.88 | KDM1A (0.38) | ALDH1A1KDM1AMAOAMAOBMEN1 | |
| SCHEMBL1268495 | 0.85 | TRPC6 (0.37) | TRPC6L3MBTL3L3MBTL1ALDH1A1TRPC3 | |
| SCHEMBL1268498 | 0.85 | TRPC6 (0.37) | TRPC6L3MBTL3L3MBTL1ALDH1A1TRPC3 | |
| SCHEMBL25602165 | 0.85 | TRPC6 (0.37) | TRPC6L3MBTL3L3MBTL1ALDH1A1TRPC3 | |
| SCHEMBL23952173 | 0.83 | TRPC6 (0.40) | TRPC6ALDH1A1TRPC3KDM1AMAOA | |
| Hydrochloric Acid SCHEMBL26118647 | 0.83 | ALDH1A1 (0.39) | TRPC6L3MBTL3L3MBTL1ALDH1A1TRPC3 | |
| SCHEMBL26116430 | 0.83 | TRPC6 (0.40) | TRPC6ALDH1A1TRPC3KDM1AMAOA | |
| SCHEMBL13880300 | 0.83 | DPP4 (0.40) | TRPC6HTR6ALDH1A1TRPC3KDM1A | |
| Hydrochloric Acid SCHEMBL26118645 | 0.83 | ALDH1A1 (0.39) | TRPC6L3MBTL3L3MBTL1ALDH1A1TRPC3 | |
| Hydrochloric Acid SCHEMBL30932819 | 0.81 | TRPC6 (0.39) | TRPC6ALDH1A1TRPC3KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148029-A2 | ORGANIC COMPOUNDS AS NLRP3 INHIBITORS | KODIAK SCIENCES INC. (US) | 2024-07-11 | — | — | WO | disclosed |