Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.44 |
| ▸ | MAOB | P27338 | 8/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21941329 | 0.98 | HRH3 (0.43) | HRH3MAOBPSMB1PSMB5PSMB2 | |
| SCHEMBL21667940 | 0.84 | KDM4E (0.40) | HRH3MAOBPSMB1PSMB5PSMB2 | |
| SCHEMBL20332900 | 0.84 | HRH3 (0.43) | HRH3MAOBPSMB1PSMB5PSMB2 | |
| SCHEMBL31617090 | 0.82 | HRH3 (0.39) | HRH3MAOB | |
| SCHEMBL31617064 | 0.82 | HRH3 (0.39) | HRH3MAOB | |
| SCHEMBL18650122 | 0.82 | PSMB1 (0.45) | HRH3MAOBPSMB1PSMB5PSMB2 | |
| SCHEMBL21348351 | 0.81 | HRH3 (0.42) | HRH3MAOB | |
| SCHEMBL21667967 | 0.81 | LTA4H (0.43) | HRH3MAOB | |
| SCHEMBL10223194 | 0.80 | KDM4E (0.43) | HRH3MAOBPSMB1PSMB5PSMB2 | |
| SCHEMBL21667821 | 0.80 | LTA4H (0.45) | HRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036319-B2 | Polyvalent sting activating compositions and uses thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12036319-B2 | Polyvalent sting activating compositions and uses thereof | STING1, CGAS, TLR7 | HRH3 2151/4885MAOB 4818/4885PSMB1 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.