Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 5/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29307956 | 0.86 | PDE10A (0.42) | PDE10AESR1ESR2PRKDCCTDSP1 | |
| SCHEMBL29307849 | 0.84 | ESR1 (0.48) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL29307843 | 0.83 | NPC1 (0.47) | PDE10AESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL29307902 | 0.81 | PDGFRB (0.45) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL29307865 | 0.81 | KDM4E (0.43) | ESR1ESR2GSK3BKDM4EALDH1A1 | |
| SCHEMBL29307844 | 0.79 | RAC1 (0.47) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL29307846 | 0.78 | RAC1 (0.43) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL21382500 | 0.77 | PDE10A (0.38) | PDE10APRKDCCTDSP1KDM4EALDH1A1 | |
| SCHEMBL29307850 | 0.76 | PDGFRB (0.47) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL29307847 | 0.72 | SMN1; SMN2 (0.39) | ESR1ESR2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12041850-B2 | Luminescent compounds | Chromatwist Limited (GB) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12041850-B2 | Luminescent compounds | AHR, ARNT, CYCS | PDE10A 2108/4885ESR1 409/4885ESR2 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.