Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10088095 | 1.00 | CA1 (0.40) | CA1CA2ZDHHC7MAPTHTT | |
| SCHEMBL29308554 | 1.00 | CA1 (0.40) | CA1CA2ZDHHC7MAPTHTT | |
| SCHEMBL14003053 | 0.87 | HTT (0.36) | MAPTHTTSMN1; SMN2HSD17B10HDAC1 | |
| SCHEMBL9327185 | 0.87 | HTT (0.36) | MAPTHTTSMN1; SMN2HSD17B10HDAC1 | |
| SCHEMBL21261493 | 0.86 | CA1 (0.38) | CA1CA2MAPTHTTSMN1; SMN2 | |
| SCHEMBL15382587 | 0.86 | CA1 (0.38) | CA1CA2MAPTHTTSMN1; SMN2 | |
| SCHEMBL2332745 | 0.86 | CA1 (0.38) | CA1CA2MAPTHTTSMN1; SMN2 | |
| SCHEMBL10088094 | 0.85 | GABRR1 (0.32) | CA1CA2CA14CA12CA7 | |
| SCHEMBL700951 | 0.84 | HDAC1 (0.39) | CA2MAPTHDAC1HDAC2CHRM1 | |
| SCHEMBL701747 | 0.84 | HDAC1 (0.39) | CA2MAPTHDAC1HDAC2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036289-B2 | Gadolinium bearing PCTA-based contrast agents | BRACCO IMAGING S.P.A. (IT) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12036289-B2 | Gadolinium bearing PCTA-based contrast agents | GLRX3, GLRA1, GRHPR | CA1 482/4885CA2 491/4885ZDHHC7 2876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.