Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23084630 | 0.84 | NPC1 (0.35) | ADAM17CYP1A2 | |
| SCHEMBL14559779 | 0.74 | TACR1 (0.32) | — | |
| SCHEMBL22650959 | 0.73 | NPC1 (0.36) | CYP1A2 | |
| SCHEMBL17485425 | 0.72 | RAB9A (0.39) | CYP1A2 | |
| SCHEMBL29166083 | 0.70 | SLC13A5 (0.38) | CYP1A2SLC13A5 | |
| SCHEMBL22651406 | 0.69 | ELANE (0.38) | CYP1A2 | |
| SCHEMBL21155600 | 0.68 | KMT2A (0.36) | CYP1A2SLC13A5 | |
| SCHEMBL23084629 | 0.67 | CHRM2 (0.34) | CYP1A2 | |
| SCHEMBL24496166 | 0.67 | KCNH2 (0.36) | CYP1A2 | |
| SCHEMBL24604432 | 0.66 | NPC1 (0.35) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228503-A1 | TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228503-A1 | TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS | SSB, CGAS, STING1 | ADAM17 4143/4885CYP1A2 1153/4885SLC13A5 3369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.