Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26024103 | 0.83 | HTT (0.35) | KMT2AMEN1CYP1A2MAPTLMNA | |
| SCHEMBL29868093 | 0.81 | ALDH1A1 (0.36) | KDM4EGAAMAPTMAPK1LMNA | |
| SCHEMBL23541501 | 0.81 | KCNA5 (0.41) | KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL23084689 | 0.81 | POLB (0.35) | KMT2ALMNAL3MBTL1GMNNALDH1A1 | |
| SCHEMBL23084690 | 0.81 | ALDH1A1 (0.36) | KDM4EGAAMAPTMAPK1LMNA | |
| SCHEMBL23084702 | 0.81 | MEN1 (0.38) | KMT2AMEN1KDM4EGAAMAPK1 | |
| SCHEMBL29868015 | 0.81 | MEN1 (0.38) | KMT2AMEN1KDM4EGAAMAPK1 | |
| SCHEMBL20712022 | 0.79 | CASP3 (0.32) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25432478 | 0.79 | MMP13 (0.34) | KMT2A | |
| SCHEMBL14559779 | 0.78 | TACR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113861107-A | Preparation method of isavuconazole sulfate intermediate | 开封明仁药业有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-119192067-A | Preparation method of isaconazole side chain intermediate C1 | 山东齐都药业有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-113861107-A | Preparation method of isavuconazole sulfate intermediate | 开封明仁药业有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-113861107-A | Preparation method of isavuconazole sulfate intermediate | 开封明仁药业有限公司 | 2021-12-31 | — | — | CN | disclosed |
| US-20210070698-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE | BRISTOL-MYERS SQUIBB COMPANY | 2021-03-11 | — | — | US | disclosed |
| WO-2019136112-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070698-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE | IDO1, IDO2, INMT | KMT2A 446/4885MEN1 1033/4885KDM4E 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.