SCHEMBL293104

SCHEMBL293104

C=CC(C)=Cc1cccc(Nc2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.47
ALDH1A1 P00352 4/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
AR P10275 1/20 0.47
TSHR P16473 3/20 0.44
CYP3A4 P08684 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TDP1 Q9NUW8 2/20 0.41
LMNA P02545 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
GFER P55789 1/20 0.41
BTK Q06187 1/20 0.39
HSD17B10 Q99714 4/20 0.39
POLB P06746 1/20 0.39
SIRT1 Q96EB6 1/20 0.38
MAPK1 P28482 2/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18173489 0.78 ALDH1A1 (0.61) MAPTALDH1A1KMT2ATSHRCYP3A4
SCHEMBL9142807 0.78 ALDH1A1 (0.61) MAPTALDH1A1KMT2ATSHRCYP3A4
SCHEMBL293105 0.77 MAPT (0.47) MAPTALDH1A1MEN1KMT2AAR
SCHEMBL8626310 0.74 FBP1 (0.66) MAPTALDH1A1MEN1KMT2AAR
SCHEMBL8626306 0.74 FBP1 (0.66) MAPTALDH1A1MEN1KMT2AAR
Styrene SCHEMBL10790042 0.73 ALDH1A1 (0.58) MAPTALDH1A1KMT2ATSHRCYP3A4
SCHEMBL19915079 0.73 NPSR1 (0.47) MAPTALDH1A1TSHRCYP3A4NPSR1
SCHEMBL19921884 0.73 NPSR1 (0.47) MAPTALDH1A1TSHRCYP3A4NPSR1
SCHEMBL293164 0.72 MAPT (0.40) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL16500818 0.71 ALDH1A1 (0.52) MAPTALDH1A1MEN1KMT2AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
WO-2020054484-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT 株式会社ブリヂストン 2020-03-19 WO disclosed
US-20180244808-A1 METHOD FOR PRODUCING MODIFIED DIENE-BASED RUBBER, RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2018-08-30 US disclosed
EP-3345933-A1 METHOD FOR PRODUCING MODIFIED DIENE RUBBER, RUBBER COMPOSITION, AND TIRE Bridgestone Corporation (JP) 2018-07-11 EP disclosed
EP-3029099-B1 RUBBER COMPOSITION AND TIRE PRODUCED USING SAME, AND PROCESS OF PRODUCING RUBBER COMPOSITION BRIDGESTONE CORP (JP) 2018-04-04 EP disclosed
EP-2845869-B1 MODIFIED NATURAL RUBBER, METHOD FOR PRODUCING SAME, RUBBER COMPOSITION, AND TIRE BRIDGESTONE CORP (JP) 2018-01-17 EP disclosed
EP-2799482-B1 Rubber composition and tire produced using same, and process of producing rubber composition BRIDGESTONE CORP (JP) 2017-03-29 EP disclosed
US-9428619-B2 Interpolymers containing isobutylene and diene mer units BRIDGESTONE CORPORATION (JP) 2016-08-30 US disclosed
US-20160168365-A1 PROCESS OF PRODUCING RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2016-06-16 US disclosed
EP-3029099-A1 RUBBER COMPOSITION AND TIRE PRODUCED USING SAME, AND PROCESS OF PRODUCING RUBBER COMPOSITION Bridgestone Corporation (JP) 2016-06-08 EP disclosed
EP-1215226-B1 Diene-based rubber/inorganic compound complexes, methods for producing the same and rubber compositions containing the same JSR CORP (JP) 2006-06-07 EP disclosed
EP-1629021-A1 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2006-03-01 EP disclosed
US-20050182159-A1 Diene rubber-inorganic compound composite and process for producing the same JRS CORPORATION (JP) 2005-08-18 US disclosed
EP-1500679-A1 DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2005-01-26 EP disclosed
WO-2004106397-A1 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2004-12-09 WO disclosed
US-6740704-B2 UNIFORM DISPERSION JSR CORPORATION (JP) 2004-05-25 US disclosed
US-20040030027-A1 Diene rubber/inorganic compound composite and method for producing the same and rubber composition BRIDGESTONE CORPORATION (JP) 2004-02-12 US disclosed
EP-1323775-A1 DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND METHOD FOR PRODUCING THE SAME AND RUBBER COMPOSITION JSR Corporation (JP) 2003-07-02 EP disclosed
US-20020111418-A1 Methods for producing diene-based rubber/inorganic compound complexes and rubber compositions containing the same JSR CORPORATION (JP) 2002-08-15 US disclosed
EP-1215226-A2 Diene-based rubber/inorganic compound complexes, methods for producing the same and rubber compositions containing the same JSR Corporation (JP) 2002-06-19 EP disclosed