Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 16/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 16/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412532 | 1.00 | HCRTR2 (0.43) | HCRTR2HCRTR1MEN1KMT2A | |
| SCHEMBL3417003 | 0.88 | HCRTR1 (0.45) | HCRTR2HCRTR1 | |
| SCHEMBL2931897 | 0.88 | HCRTR1 (0.45) | HCRTR2HCRTR1 | |
| SCHEMBL3414068 | 0.87 | MEN1 (0.43) | HCRTR2HCRTR1MEN1KMT2A | |
| SCHEMBL2926961 | 0.87 | MEN1 (0.43) | HCRTR2HCRTR1MEN1KMT2A | |
| SCHEMBL2930541 | 0.85 | HCRTR1 (0.46) | HCRTR2HCRTR1 | |
| SCHEMBL3415643 | 0.85 | HCRTR1 (0.46) | HCRTR2HCRTR1 | |
| SCHEMBL3415834 | 0.84 | HCRTR1 (0.46) | HCRTR2HCRTR1 | |
| SCHEMBL2925288 | 0.84 | HCRTR1 (0.46) | HCRTR2HCRTR1 | |
| SCHEMBL2931084 | 0.84 | HCRTR2 (0.44) | HCRTR2HCRTR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079690-B1 | 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-09-15 | — | — | EP | disclosed |