Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 11/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3415834 | 1.00 | HCRTR1 (0.46) | HCRTR1HCRTR2HTR2CSLC6A4SLC6A3 | |
| SCHEMBL2448756 | 0.92 | HCRTR1 (0.43) | HCRTR1HCRTR2HTR2CSLC6A4SLC6A3 | |
| SCHEMBL2930541 | 0.92 | HCRTR1 (0.46) | HCRTR1HCRTR2TSHRRECQL | |
| SCHEMBL3415643 | 0.92 | HCRTR1 (0.46) | HCRTR1HCRTR2TSHRRECQL | |
| SCHEMBL2931897 | 0.90 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL2924532 | 0.90 | SLC6A4 (0.40) | HCRTR1HCRTR2SLC6A4SLC6A3MLNR | |
| SCHEMBL3417003 | 0.90 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL2931383 | 0.89 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL3416000 | 0.89 | HCRTR1 (0.50) | HCRTR1HCRTR2CDK4CCND1 | |
| SCHEMBL2448801 | 0.88 | HCRTR1 (0.50) | HCRTR1HCRTR2SLC6A4SLC6A3MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079690-B1 | 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-09-15 | — | — | EP | claimed |
| EP-2079690-B1 | 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-09-15 | — | — | EP | disclosed |