SCHEMBL2931143

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31577730	0.90	CFTR (0.57)	CFTRPPARGPPARDPPARATDP1
	SCHEMBL12630099	0.82	CFTR (0.57)	CFTRPPARGPPARDPPARATDP1
	SCHEMBL5620982	0.82	ESR1 (0.49)	PPARGPPARDPPARAESR1IDH1
	SCHEMBL958734	0.81	CYP2C19 (0.53)	CFTRTDP1CYP2C19CYP1A2CYP2C9
	SCHEMBL12100459	0.81	TDP1 (0.52)	TDP1CYP1A2CYP2C9ALDH1A1HPGD
	SCHEMBL2226597	0.81	TDP1 (0.48)	TDP1CYP2C19CYP1A2CYP2C9ALDH1A1
	SCHEMBL5277497	0.80	ESR1 (0.50)	PPARGPPARDPPARAESR1CYP2C19
	SCHEMBL25336183	0.79	CFTR (0.54)	CFTRPPARGPPARDPPARACYP2C19
	SCHEMBL1451872	0.79	CFTR (0.53)	CFTRPPARGPPARDPPARATDP1
	SCHEMBL5320603	0.78	MRGPRX4 (0.57)	PPARDPPARAESR1TDP1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.