SCHEMBL1451872

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12630099	0.88	CFTR (0.57)	CFTRPPARGPPARDPPARAKDM4E
	SCHEMBL31577730	0.85	CFTR (0.57)	CFTRPPARGPPARDPPARAKDM4E
	SCHEMBL12824608	0.85	CFTR (0.53)	CFTRPPARGPPARDPPARAKDM4E
	SCHEMBL24901813	0.79	CFTR (0.67)	CFTRMAPTKDM4EKMT2AMRGPRX4
	SCHEMBL2931143	0.79	CFTR (0.52)	CFTRPPARGPPARDPPARAKDM4E
	SCHEMBL2365399	0.79	CFTR (0.52)	CFTRMAPTKDM4EHTTKMT2A
	SCHEMBL20471847	0.78	CFTR (0.55)	CFTRMAPTKDM4EHTTKMT2A
	SCHEMBL2006511	0.77	EGFR (0.46)	CFTRMAPTKDM4EHTTKMT2A
	SCHEMBL953081	0.77	PTGDR2 (0.55)	PPARGPPARDPPARAKDM4EPTGDR2
	SCHEMBL5943417	0.75	KDM4E (0.73)	CFTRMAPTKDM4EKMT2AMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.